Intestinal Disorders

Dear Member of the Intestinal Disorders Section and interested others:

We thank you for attending the 41st annual DDW® in New Orleans, LA and making it a scientifically relevant and exciting meeting! If you have specific feedback regarding speakers sponsored by the Intestinal Disorders (ID) Section at DDW, please share your thoughts with us. We will do our best to consider your comments and concerns as we plan our program for next DDW 2011 in Chicago.

Two of our section's abstracts were presented in the highly successful AGA plenary sessions. "Efficacy and Safety of Once Daily Linaclotide Administered Orally for 12-Weeks in Patients with Chronic Constipation: Results from 2 Randomized, Double-blind, Placebo-controlled Phase 3 Trials" was presented at the main AGA Institute Clinical Science Plenary Session. "Altered Gut Microbiota in Toll-Like Receptor-5 (TLR5) Deficient Mice Results in Metabolic Syndrome" was presented at the main AGA Institute Basic Science Plenary Session.

This year the ID section accepted the majority of the abstracts submitted. The accepted abstracts were designated as oral or poster presentations and of distinction based on their ranking by our dedicated abstract reviewers.

ID Abstract Selection 2010
Total Abstracts submitted 382
Accepted Abstracts 341
Oral Presentations 72
Posters 269
Posters of Distinction 27

ID sponsored Clinical, Translational, and Research Symposia, and abstract based Research and Topic Fora, as well as one State of the Art Lecture. New this year the ID section sponsored Barrier and Immune Function of the Intestinal Epithelium: An Interactive Topic Forum on May 4, 2010 from 2:15 - 3:45pm. This session included a panel discussion and highlighted abstracts representing this year's greatest scientific advancements in this particular field. Below is a listing of the ID section programing for 2010 with the level of attendance indicated. As you can see, in general, ID sessions were extremely well attended this year.

ID Sessions
Sunday, May 2, 2010 Attendance
Research Forum: Gut Microbes And Disease 8:30am-10:00am 75
Translational Symposium: Pathogenesis and Evaluation of Fibrosis in the Digestive System 10:30am-12:00pm 80
Research Symposium: Mechanisms and Novel Imaging Modalities of Injury and Repair in the Intestinal Epithelial Barrier 2:15pm-3:45pm 190
Research Symposium: Intestinal Inflammation Injury Repair And Fibrosis 2:15pm-3:45pm 80
Cross-Sectional Topic Forum: Prebiotics and Probiotics in the Intestine: Activities and Function 4:00pm-5:30pm 150
Research Forum: Intestinal Epithelial Transport: Absorption And Secretion I 4:00pm-5:30pm 100
Monday, May 3, 2010
SOA Lecture: Epithelial Mesenchymal Transition (EMT) in Development and Disease 2:15pm-3:15pm 180
Research Forum: Celiac Disease 2:15pm-3:15pm 200
Topic Forum: Ischemia, Hypoxia, and the Vasculature in Intestinal Inflammation 4:00pm-5:30pm 100
Intestinal Disorders Section Business Meeting 5:30pm-6:30pm unknown
Tuesday, May 4, 2010
Sunrise Session: Advances in Epithelial Transport 7:00am-8:00am 50
Research Forum: Tight Junctions Regulation Of Barrier Function And Wound Repair 8:30am-10:00am 150
Research Forum: Mechanisms of Intestinal Epithelial Homeostasis 8:30am-10:00am 85
Clinical Symposium: Diagnosis and Highly Effective Medical Management of Celiac Disease 10:30am-12:00pm 500
Research Forum: Intestinal Inflammatory Disease: Novel Diagnostics And Therapeutics 10:30am-12:00pm 65
Barrier and Immune Function of the Intestinal Epithelium: An Interactive Topic Forum 2:15pm-3:45pm 310
Clinical Symposium: Difficult Diarrheas 2:15pm-3:45pm 475
Research Forum: Functional and Motility Related Intestinal Disorders: Novel Diagnostics and Therapeutics 2:15pm-3:45pm 75
Wednesday, May 5, 2010
Sunrise Session: Advances in Celiac Disease 7:00am-8:00am 50
Topic Forum: Intestinal Epithelial Gene Regulation And Signal Transduction 8:30am-10:00am 65
Cross-Sectional Topic Forum: Genetics and Intestinal Disorders 8:30am-10:00am 25
Research Forum: Intestinal Epithelial Transport: Absorption And Secretion II 10:30am-12:00pm 50

Each June, ID section descriptors are reviewed to optimize scientific relevance and minimize overlapping topics with other AGA Institute Sections and to encourage both clinical research and basic science abstract submissions. The current list of abstract descriptors is as follows. (ID descriptors may change as we go forward to DDW 2011.) We would like to thank our abstract review Committee Chairs and members for generously sharing their expertise and time in order to ensure that the most novel and relevant developments in Intestinal Disorders were shared at DDW.

Descriptor Name Abstracts Received Abstract Review Chair Abstract Reviewers
Clinical Intestinal Disorders 47 Donald Kotler Robert Craig, Faten Aberra, David Binion
Celiac Disease: Basic Mechanisms 8 Sheila Crowe Alessio Fassano, Bana Jabri, Daniel Leffler
Celiac Disease: Clinical 32 Sheila Crowe Alessio Fassano, Bana Jabri, Daniel Leffler
Diarrhea and Malabsorption 9 Donald Kotler Robert Craig, Faten Aberra, David Binion
Novel Diagnostics and Therapeutics in Intestinal Disease 25 Michael Camilleri Jay Pasricha, James Lewis, Carol Semrad
Pharmacotherapy and the Intestine 24 Michael Camilleri Jay Pasricha, James Lewis, Carol Semrad
Basic and Clinical Aspects of Ischemia and Hypoxia 17 Thaddeus Stappenbeck Elke Cario, Jan-Michael Klapproth, Peter Higgins
Intestinal Inflammation, Injury, Repair, and Fibrosis 39 Thaddeus Stappenbeck Elke Cario, Jan-Michael Klapproth, Peter Higgins
Murine Models of Intestinal Disorders 12 Shanthi Sitaraman Kris Steinbrecher, Shrikant Anant, Christian Jobin, Declan McCole
Intestinal Microbiota: Microbial Pathogenesis and Commensals 18 Andrew Gewirtz Mitchell Cohen, Nita Salzman, Beth McCormick
GI Infections 34 Andrew Gewirtz Mitchell Cohen, Nita Salzman, Beth McCormick
Intestinal Cell and Molecular Biology 10 Shanthi Sitaraman Kris Steinbrecher, Shrikant Anant, Christian Jobin, Declan McCole
Intestinal Epithelial Transport: Absorption and Secretion 44 Michael Dwinell Le Shen, Lara Gawenis, Stephen Keely
Tight Junctions, Regulation of Barrier Function and Wound Repair 28 Michael Dwinell Le Shen, Lara Gawenis, Stephen Keely
Intestinal Epithelial Cell Signal Transduction and Gene Regulation 14 Shanthi Sitaraman Kris Steinbrecher, Shrikant Anant, Christian Jobin, Declan McCole
Prebiotics and Probiotics (Cross-section descriptor) 13 Karen Madsen Andrew Gewirtz, Elena Verdu, Martin Floch
Stem Cell Biology (Cross-section descriptor) 1 Michael Choi Steve Cohn, Bart Rountree, Tim Wang, Courtney Houchen
Genetics and Intestinal Disorders (Cross-section descriptor) 7 William Grady Rhonda Souza, Shanthi Sitaraman

Section leaders will review committee membership this summer for abstract review committees to confirm the final composition for DDW 2011 committees.

Here are three ways to get involved:

  1. If you are interested in serving as a reviewer for any of our abstract descriptors, please let us know. Please cite the abstract descriptor for which you would be interested in reviewing. Please recommend any new descriptors for abstracts.
  2. Please submit your invaluable ideas about the topics and invited speakers that you would like to hear at next year's DDW. The more specific you can be, the better (title, individual talks, speakers, learning objectives). Please forward your suggestions to John Whiton, AGA Institute by July 6, 2010.
  3. Members interested in participating in the various activities of the Section should contact us at the addresses below. We are particularly interested in increasing participation by junior investigators/clinicians and international members at this time.

Thank you for your continuing strong support of the Intestinal Disorders Section.

Sincerely,

Gary D. Wu, MD
Chair, ID Section, AGA Institute Council

Jerrold R. Turner, MD, PhD, AGAF
Vice-Chair, ID Section, AGA Institute Council