2013-04-02 12:37:09 UTC

CRC Screening Interval After Negative Colonoscopy

April 4, 2013

Steven Nakao and colleagues conclude in Surgical Endoscopy that a period less than than 10 years for routine colonoscopy may be necessary, specifically in the 50–80-year age group.

Despite the high sensitivity of screening colonoscopy, polyps and cancers can still go undetected. With the polyp-to-cancer transformation cycle averaging seven to 10 years, present guidelines recommend repeat colonoscopy within 10 years after negative screening. Steven Nakao and colleagues evaluated the incidence and pathology of colorectal cancers (CRC) following a previous negative screening colonoscopy. They report in Surgical Endoscopy that 18 percent of the total study population had newly discovered CRC within a five-year colonoscopy screening period. Most of these malignancies were found within the 50–80-year age group and located predominantly in the right colon and distally in the sigmoid and rectum. The researchers conclude that a shorter period for routine colonoscopy may be considered.

Surgical Endoscopy 2013: 3(27): 768-773

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