2010-06-02 13:34:15 UTC

Diagnostic Testing for Celiac Disease Among Patients with Abdominal Symptoms

June 2, 2010

The symptoms and consequences of celiac disease usually resolve with a lifelong gluten-free diet. However, clinical presentation is variable and most patients presenting with abdominal symptoms in primary care will not have celiac disease, and unnecessary diagnostic testing should be avoided. According to results published in the Journal of the American Medical Association, among adult patients presenting with abdominal symptoms in primary care or other unselected populations, IgA antitissue transglutaminase antibodies and IgA antiendomysial antibodies have high sensitivity and specificity for diagnosing celiac disease.



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