2016-04-25 19:28:52 UTC

New Recommendation: H. Pylori Therapies Should Be Given for 14 Days

April 26, 2016

The Toronto Consensus for the treatment of H. Pylori, published in Gastroenterology, stresses careful attention to local antibiotic resistance and eradication patterns.

Helicobacter pylori (H. pylori) infection is increasingly difficult to treat. Due to the increasing prevalence of antibiotic-resistant strains and evidence of more frequent failures of triple therapies — as well as the existence of new therapies — the Canadian Association of Gastroenterology and the Canadian Helicobacter Study Group determined that an updated consensus statement was needed.

This new consensus statement — now available as a Gastroenterology article in press — reviews the literature and provides specific, updated recommendations for eradication therapy in adults.

In the statement, the authors conclude that optimal treatment of H. pylori requires careful attention to local antibiotic resistance and eradication patterns. Based on evidence of higher eradication with regimens of longer duration, and increasing failure of shorter treatment durations, the consensus group strongly recommended that all H. pylori eradication regimens be given for 14 days.

The group also states that concomitant non-bismuth quadruple therapy or traditional quadruple bismuth therapy should play a more prominent role in H. pylori eradication.

Read the full recommendations in Gastroenterology (login required). 

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