2014-06-10 19:07:00 UTC

Probiotics Prevent Hepatic Encephalopathy in Patients With Cirrhosis

June 12, 2014

Manish Kumar Lunia and colleagues report in Clinical Gastroenterology and Hepatology that, based on a prospective, randomized controlled trial, probiotics were found to be effective in preventing hepatic encephalopathy in patients with cirrhosis.

Hepatic encephalopathy (HE) is associated with a poor prognosis in patients with advanced liver disease. Probiotics alter the intestinal microbiota with non–urease-producing organisms that reduce production of ammonia. Manish Kumar Lunia and colleagues investigated the efficacy of probiotics for the primary prophylaxis of HE. They report in Clinical Gastroenterology and Hepatology that, based on a prospective, randomized controlled trial, probiotics were found to be effective in preventing HE in patients with cirrhosis.

Clinical Gastroenterology and Hepatology 2014: 12(6): 1003-1008.e1

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