2015-01-06 19:34:32 UTC

System to Culture Human Gastric Organoid

Jan. 8, 2015

Publishing in Gastroenterology, Sina Bartfeld and colleagues describe conditions required for long-term three-dimensional culture of human gastric stem cells, which provides insight into H. pylori infection and other gastric pathologies.

Sina Bartfeld and colleagues previously established long-term, three-dimensional culture of organoids from mouse tissues (intestine, stomach, pancreas and liver) and human intestine and pancreas. Publishing in Gastroenterology, they describe conditions required for long-term three-dimensional culture of human gastric stem cells. The researchers developed a system to culture human gastric organoids. This system can be used to study H. pylori infection and other gastric pathologies.

Gastroenterology 2015: 148(1): 126-136.e6

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