AGA Institute GastroSlides Unit on Pancreatic Physiology and Pancreatitis
“Pancreatic Physiology and Pancreatitis” is separated into the following sections: Part I: Pancreatic Physiology and Biology I; Part II: Pancreatic Physiology and Biology II; Part III: Acute Pancreatitis I; Part IV: Acute Pancreatitis II; Part V: Chronic Pancreatitis; Part VI: Pancreatic Disease Cases, Including Acute Pancreatitis, Chronic Pancreatitis and Pancreatic Neoplasms. Moreover, two movies are included: normal ERCP and ERCP with papillotomy and extraction of common duct stones.
The images illustrate the physiology and pathophysiology of pancreatic function and the causes, diagnosis and management of acute and chronic pancreatitis. The outstanding photographs, micrographs, illustrations and movies explain important concepts in our understanding of how the pancreas functions and serve to add a scientific basis to the treatment of inflammation and other conditions affecting this vital organ. Images, including graphic representations of data from key studies, are accompanied by explanatory legends that contain recent literature citations, thereby providing a unique teaching and self-educational resource. The senior author, Fred Gorelick, MD, is a professor of medicine and cell biology, Yale University School of Medicine, New Haven, CT.
About the Instructors
Fred Gorelick, MD, is a professor of medicine (digestive diseases) and cell biology at Yale University School of Medicine and VA Connecticut in West Haven, CT. Dr. Gorelick studies the mechanisms of pathologic zymogen activation in the pancreatic acinar cell, cell signaling and intracellular targeting, and he is supported by grants from the Department of Veterans Affairs and National Institutes of Health (NIH).
Lars Fischer, MD, is a surgical trainee at Chirurgische Universitätsklinik, Heidelberg, Germany. The focus of his scientific work concerns the effects of phosphatidylinositol 3-kinase on pancreatitis and calcium signaling in pancreatic acinar cells.
Anil Nagar, MD, is an assistant professor of medicine (digestive diseases) at Yale University School of Medicine and VA Connecticut in West Haven, CT. Dr. Nagar is interested in clinical studies that examine the value of interventions for detecting and treating GI diseases.
Stephen Pandol, MD, is a professor of medicine (gastroenterology) at UCLA and the VA Greater Los Angeles Healthcare System. Dr. Pandol studies the cellular mechanisms of pancreatitis and is particularly interested in the role of inflammation and the regulation of cell death and cell signaling. Dr. Pandol’s research is supported by grants from the Department of Veterans Affairs and NIH.
Guillermo Robles-Diaz, MD, is a professor of medicine in the Department of Medicine and Experimental Medicine at Universidad Nacional Autónoma de México, Mexico City. Dr. Robles-Diaz studies the factors that affect the prognosis of acute pancreatitis and the treatment of chronic pancreatitis.
Akihiko Sato, MD, is an assistant professor in the Division of Gastroenterology, Tohoku University Graduate School of Medicine, Sendai, Japan. He is interested in the pathophysiology of acute pancreatitis.
Mark Topazian, MD, is an associate professor of medicine (digestive diseases) at the Mayo Clinic in Rochester, MN. Dr. Topazian studies clinical issues related to the diagnosis of pancreatic and biliary tract disease by clinical and imaging modalities.
Jerry Schoendorf, MAMS
Chapel Hill, NC
The authors thank authors and reviewers of previous pancreatic physiology and pancreatitis slide sets. Dr. Tooru Shimosegawa, Tohoku University Graduate School of Medicine, Sendai, Japan, is recognized for his contributions to slides related to autoimmune pancreatitis. Finally, we wish to give special recognition to the AGA Institute for supporting this didactic presentation and to Jean-Pierre Raufman for his leadership, enthusiastic support and tireless efforts to help make this an accurate and internationally valued educational tool.
The content included in this GastroSlide set, Pancreatic Physiology and Pancreatitis, was published on May 5, 2006. This slide set has not been updated since the date of publication and is provided “as is.” It is the learner's responsibility to evaluate the accuracy of any information found within these educational materials.
The intent of this series is to provide individual clinicians and educators with materials to use in their educational activities, such as lecturing at continuing medical education meetings and for self-education. AGA encourages all uses of GastroSlide materials consistent with this objective.
Materials are to be displayed in the same content and form as the original with no alterations unless approved by AGA. No materials may be reproduced for any purpose without written permission of AGA. Materials may only be used for educational purposes and may not be used to promote or advertise any pharmaceutical, medical device or organization.