AGA Institute GastroSlides Unit on Pancreatitis (Japanese Version)
“Pancreatitis” is separated into the following sections: Part 1: Pancreatic Physiology and Biology; Part 2: Acute Pancreatitis I; Part 3: Acute Pancreatitis II; Part 4: Chronic Pancreatitis; Part 5: Pancreatic Disease Cases, Including Acute Pancreatitis, Chronic Pancreatitis and Pancreatic Neoplasms. Moreover, two movies are included: normal ERCP and ERCP with papillotomy and extraction of common duct stones.
This teaching unit represents a set of images that illustrate the physiology and pathophysiology of pancreatic function and the causes, diagnosis and management of acute and chronic pancreatitis. The outstanding photographs, micrographs, illustrations and movies explain important concepts in our understanding of how the pancreas functions. Images, including graphic representations of data from key studies, are accompanied by explanatory legends that contain recent literature citations, thereby providing a unique teaching and self-educational resource. The senior author, Fred Gorelick, MD, is a professor of medicine and cell biology, Yale University School of Medicine, New Haven, CT.
About the Instructors
Fred Gorelick is a professor of medicine (digestive diseases) and cell biology at Yale University School of Medicine, New Haven, CT. Dr. Gorelick did a GI fellowship at Yale University and joined the Yale faculty in 1979. He received research training with James D. Jamieson and Paul Greengard. Dr. Gorelick studies the mechanisms of pathologic zymogen activation in the pancreatic acinar cell, cell signaling and intracellular targeting. His research is supported by grants from the Department of Veterans Affairs and National Institutes of Health (NIH).
Dr. Stephen Pandol is a professor of medicine at UCLA. Dr. Pandol did his GI clinical fellowship at UCLA with Jon Isenberg and received his research training at NIH with Jerry Gardner and Robert Jensen. He joined the faculty at UCSD in 1982 and moved to UCLA and the VA Greater Los Angeles Healthcare System in 1996. Dr. Pandol studies the cellular mechanisms of pancreatitis and pancreatic cancer and is particularly interested in mechanisms of inflammation and cell death in these disorders. Dr. Pandol’s research is supported by grants from the Department of Veterans Affairs and NIH.
Dr. Mark Topazian is an associate professor of medicine at the Mayo College of Medicine in Rochester, MN. Dr. Topazian did his GI training at UCSF and was on the faculty at the Yale School of Medicine until 2003. Dr. Topazian studies clinical issues related to the endoscopic and medical diagnosis and treatment of pancreatic and biliary tract disease.
Dr. Tooru Shimosegawa is a professor of medicine (gastroenterology) at Tohoku University Graduate School of Medicine. Dr. Shimosegawa did his GI fellowship and received his research training at Tohoku University School of Medicine under the direction of former professors Yoshio Goto and Takayoshi Toyota. He joined the faculty at Tohoku University School of Medicine in 1989. Dr. Shimosegawa studies the mechanism of MOF in severe acute pancreatitis and the pathogenesis and pathophysiology of chronic pancreatitis.
Dr. Akihiko Satoh is an assistant professor of medicine (gastroenterology) at Tohoku University Graduate School of Medicine. Dr. Satoh did his GI fellowship and received his research training at Tohoku University School of Medicine under the direction of Takayoshi Toyota and Tooru Shimosegawa. He received research training at UCLA with Stephen Pandol and Anna Gukovskaya from 2002 to 2005. Dr. Satoh studies the pathophysiology of acute pancreatitis.
Jerry Schoendorf, MAMS
Chapel Hill, NC
The authors thank the following individuals for reviewing the content of this unit and for many helpful suggestions: Minoti Apte, Peter Bonis, Peter Green, Christopher Marino, Robin Rutherford, Mark Sawicki, Carol Semrad, Stuart Spechler, Michael Steer, Helen Raybould and Jeremy Wilson. We thank Helen Shields for providing the template for clinical cases and for her helpful comments. We wish to give special recognition to David Alpers and Jean-Pierre Raufman for their leadership, enthusiastic support and tireless efforts to help make this an accurate and valued educational tool. We also acknowledge the contributions by authors of previous AGA slide sets on pancreatic physiology and pancreatitis.
This unit is dedicated to Kenneth Barwick (1947–2001). Ken was a pathologist at Yale University School of Medicine and later at the Mayo Clinic and Baptist Medical Center in Jacksonville, FL. He contributed to the training of many physicians, including gastroenterologists. Ken provided much of the pathology content of this unit. With this dedication we recognize his great contributions as an educator, physician and friend.
The content included in this GastroSlide set, Pancreatitis (Japanese Version), was published on May 30, 2005. This slide set has not been updated since the date of publication and is provided “as is.” It is the learner's responsibility to evaluate the accuracy of any information found within these educational materials.
The intent of this series is to provide individual clinicians and educators with materials to use in their educational activities, such as lecturing at continuing medical education meetings and for self-education. AGA encourages all uses of GastroSlide materials consistent with this objective.
Materials are to be displayed in the same content and form as the original with no alterations unless approved by AGA. No materials may be reproduced for any purpose without written permission of AGA. Materials may only be used for educational purposes and may not be used to promote or advertise any pharmaceutical, medical device or organization.