Hepatocellular Carcinoma

Estrogen Replacement Reduces Risk and Increases Survival Times of Women With Hepatocellular Carcinoma

Oct. 22, 2017

In a case–control study of women with HCC vs female control subjects at a single center, we associated use of estrogen MHT with reduced risk of HCC and increased overall survival times of patients with HCC.

Blog: Special 15th Anniversary Collection from Clinical Gastroenterology and Hepatology

Oct. 11, 2017

Celebrate this milestone with a look back at landmark articles, commentaries and reviews. Read more on the AGA Journals blog.

Risk of Hepatocellular Cancer in HCV Patients Treated With Direct-Acting Antiviral Agents

Oct. 1, 2017

Among HCV-infected patients treated with DAAs, SVR is associated with a considerable reduction in the risk of HCC; however, the risk for HCC remained high in patients with cirrhosis at the time of SVR.

Identification of the Consistently Altered Metabolic Targets in Human Hepatocellular Carcinoma

Sept. 1, 2017

We provide the first exposition of the consistently altered metabolic genes in HCC and show that these genes are potentially relevant targets for onward studies in preclinical and clinical contexts.

An Unusual Cause of Obscure Gastrointestinal Bleeding

Aug. 30, 2017

Why did bleeding persist in a man with a one-month history of intermittent tarry to bloody stool despite medical therapy?

Incidence and Determinants of HCC in AIH

Aug. 1, 2017

Dr. Aylin Tansel discusses her manuscript "Incidence and Determinants of Hepatocellular Carcinoma in Autoimmune Hepatitis: A Systematic Review and Meta-analysis" for the August issue of CGH. To view: http://bit.ly/2wiXgT6.

Genetic Features of Aflatoxin-Associated Hepatocellular Carcinoma

June 26, 2017

We identified specific genetic and mutation features of HCCs associated with aflatoxin exposure, including mutations in ADGRB1, compared to HCCs from general populations.
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Association of Provider Specialty and Multi-disciplinary Care With HCC Treatment and Mortality

June 1, 2017

Drs. Marina Serper and David E. Kaplan discuss their manuscript "Association of Provider Specialty and Multi-disciplinary Care With Hepatocellular Carcinoma Treatment and Mortality," for the June 2017 issue of Gastroenterology. To view manuscript click here http://bit.ly/2qkpCc5.

Association of Provider Specialty and Multidisciplinary Care With Hepatocellular Carcinoma Treatment and Mortality

June 1, 2017

We investigated patient, provider, and health system factors associated with receipt of active HCC therapy and overall survival.

Bioinformatic Search Identifies Tapeworm Drug for Treatment of Hepatocellular Carcinoma

May 31, 2017

Niclosamide identified as a potential anti-tumor agent by researchers. Read more on the AGA Journals Blog.

New Hepatitis C Treatment Not Linked to Liver Cancer

May 25, 2017

Contrary to some earlier research, most recent studies see no association between response to DAAs and HCC.

Digestive Disease Week® (DDW)

May 6, 2017

Digestive Disease Week® (DDW) is the premier meeting for the GI professional. Every year it attracts approximately 15,000 physicians, researchers and academics from around the world who desire to stay up-to-date in the field.

Hepatocellular Carcinoma Is the Most Common Indication for Liver Transplantation and Placement on the Waitlist in the United States

April 29, 2017

HCC was the leading indication for liver transplantation in the United States in 2015.

A Deep Dive Into the Different Types of Liver Cancer

March 28, 2017

A Gastroenterology review article discusses different hypotheses about the cells responsible for liver tumorigenesis. Find out more on the AGA Journals Blog.

More Funding Needed in Fight Against Deadliest Cancers

March 8, 2017

AGA calls on Congress to increase NIH funding to $34 billion in FY 2017.

Molecular Classification of Hepatocellular Adenoma Associates With Risk Factors, Bleeding, and Malignant Transformation

March 1, 2017

We aimed to update the classification system for HCA and associate the subtypes with disease risk factors and complications.

Incidence of Hepatocellular Carcinoma in All 50 United States, From 2000 Through 2012

March 1, 2017

In an analysis of the incidence of HCC in all 50 US states, we found the rate of increase in HCC to have slowed from 2010 through 2012.

A Case of Rosai-Dorfman Disease Masquerading as Cholangiocarcinoma

Feb. 28, 2017

The AGA Journals Blog recaps this challenging case published in CGH.

Natural History of Untreated Hepatocellular Carcinoma in a US Cohort and the Role of Cancer Surveillance

Feb. 1, 2017

Patients with HCCs, including those detected through surveillance, survived for short time periods in the absence of treatment, irrespective of their initial stage at diagnosis.

Mailed Outreach Program Increases Ultrasound Screening of Patients With Cirrhosis for Hepatocellular Carcinoma

Feb. 1, 2017

In a prospective study, we found outreach strategies to double the percentage of patients with cirrhosis who underwent ultrasound screening for HCC.

How Can We Study Genetic Heterogeneity Within Hepatocellular Carcinomas?

Jan. 3, 2017

Gastro researchers have developed a patient-derived cell line-based model to study how intratumor heterogeneity affects sensitivity of HCC to different therapeutic agents.

Arterial-Portal Fistula After Percutaneous Liver Biopsy in Hepatic Allograft Causing Hemobilia and Pancreatitis

Jan. 2, 2017

A 59-year-old man with HCV infection and HCC presented with acute onset epigastric pain and melena.

Cell Culture System for Analysis of Genetic Heterogeneity Within Hepatocellular Carcinomas and Response to Pharmacologic Agents

Jan. 2, 2017

We performed genetic analyses of different regions of HCCs to evaluate levels of intratumor heterogeneity and associate alterations with responses to different pharmacologic agents.

Highlighted Abstracts from the International Digestive Disease Forum

Dec. 21, 2016

CGH features 104 abstracts from the 2016 meeting, which took place in Hong Kong.