2017-06-19 20:55:26 UTC

Watch the DDW® 2017 Recap on Intestinal Disorders

July 12, 2017

New advances in treating intestinal disorders you need to know about.

The Intestinal Disorders Section leadership recapped the best takeaways from its section programming this year. Look at the three highlights below and use DDW On Demand to watch full session recordings (included in registration for attendees). Are you in the Clinical Practice Section, but didn't get to attend Digestive Disease Week® (DDW) 2017? DDW On Demand is also available for purchase.

Managing the Host-Pathogen Interface: Epithelial Innate Immunity: One of the key features in diseases of the alimentary tract depend on how the host interfaces with microbial communities. This is managed at first and most directly by mechanisms of innate immunity structured at mucosal surfaces. This session featured presentations by three of the most prominent scientists in the field: Drs. Gabriel Nunez, Gunnar Hanssen and Russel Vance. This was a truly outstanding session with new findings presented of major importance to the field of innate recognition of microbial danger. 

Barrier Functions in the Intestine and Beyond: How the single layer of epithelial cells lining the intestine forms the delicate but highly effective selective barrier separating host from environment is critical to intestinal function and host defense. A large part of the mechanisms underlying barrier function and transport of large solutes remains not well understood. In this session, three major scientists in the field — Drs. Asma Nusrat, Christina Van Itallie and Rodney Newberry — discussed aspects of the epithelial barrier that explain the pathways taken by small and large solutes that cross the barrier to effect health and disease. A lively and informative discussion of the different pathways for solute transport across the epithelial barrier ensued.  

Celiac Disease in the Postbiopsy Era: Celiac disease is highly prevalent and associated with significant morbidity. Symptoms can be hugely diverse. Methods to diagnose the disease have evolved significantly from the gold standard of years ago of three successive biopsies before gluten withdrawal, during gluten withdrawal and then after re-challenge with gluten. The approach to diagnosis and use of biopsy and other tests was discussed by three leaders in the field. The possibility to avoid biopsy in children was discussed by Dr. Steffen Husby, while the importance of biopsy in adults was addressed by Dr. Peter Green, and finally Dr. Benjamin Lebwohl addressed the follow-up of celiac disease with serology and histology.

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