2016-08-24 19:38:20 UTC

IBD Stem Cell Research Funded by AGA Research Foundation

Aug. 24, 2016

The 2016 AGA-Medtronic Research and Development Pilot Award will support Dr. Wa Xian.

Wa Xian, PhD, of the University of Texas Health Center, Houston, discussed how she will use the 2016 AGA-Medtronic Research and Development Pilot Award in Technology to support her future research on IBD using stem cells.

Read below to see more about Dr. Xian’s research or visit the AGA Research Foundation page to learn more about the award.

How will you use the funds from this award?
“The research support accompanying this award will be employed to leverage new technology developed in my laboratory for capturing “ground state” stem cells of the intestinal tract for the study of IBD.”

How will capturing “ground state” cells aid the study of IBD?
“The ability to routinely clone ground state stem cells from endoscopic biopsies of patients with IBD will provide an unlimited source of patient-specific stem cells representing very precise regions of the colon and terminal ileum and ultimately the development of stem cell lines from entire cohorts of patients linked to defined clinical histories. These model systems will [allow] unprecedented insights into whole genome expression profiles, genetic and epigenetic landscapes, and provide a platform for identifying molecules and pathways associated with chronic disease and testing new therapies based on them."

 What does this award mean to you?
“As an assistant professor and basic stem cell scientist, this award represents my first funding support towards the very dynamic and important problem of inflammatory bowel diseases.”

“I would like to express my sincere gratitude to the AGA Research Foundation for awarding me the 2016 AGA-Covidien Research and Development Pilot Award,” Dr. Xian added.

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