2010-12-17 15:14:29 UTC

Low-Dose Aspirin Use Influences Performance of FOBTs

Dec. 17, 2010

Immunochemical fecal occult blood tests (iFOBTs) are potentially promising tools for colorectal cancer (CRC) screening. Low-dose aspirin use, which increases the likelihood of gastrointestinal bleeding, is common in the target population for CRC screening. Data published in the Journal of the American Medical Association suggest that for two iFOBTs, use of low-dose aspirin compared with no aspirin was associated with a markedly higher sensitivity for detecting advanced colorectal neoplasms, with only a slightly lower specificity.

Journal of the American Medical Association; 2010: 304(22): 2513-2520

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