2016-07-25 20:37:34 UTC

The GI Research Revolution: A Look Back at 2015

July 27, 2016

CMGH has published a digital mini-issue with some of the most interesting articles from 2015.

In January 2015, AGA launched its third scientific journal, Cellular and Molecular Gastroenterology and Hepatology (CMGH), with the goal of providing a rigorous basic and translational science outlet focused on biology, physiology and immunology of the GI tract including the liver and pancreas. A year later, the journal has made great progress towards this goal.

To showcase CMGH’s first year of publishing, the editors would like to share a mini-issue with some of the most interesting articles of 2015. View the article collection on the CMGH website.

The articles included in this special year-in-review issue are representative of those CMGH published throughout the year. They include:

  • Both a comprehensive review of Barrett’s metaplasia and an original article looking at transcriptional regulation in cancers arising within Barrett’s esophagus.
  • Original studies related to intestinal disease include identification of germline mutations that lead to protein losing enteropathy and an associated editorial.
  • A report describing a new role for the neuromodulator substance P in regulating cytokine production in inflammatory cytokine production in inflammatory bowel disease. 
  • A study of enteric neuronal subtypes in a mouse model of Hirchsprung’s disease with an accompanying editorial.
  • A paper that identifies alterations in bile production and lipid homeostasis following circadian disruption.

In addition to being outstanding examples of the rigorous science you will find within each issue, these articles demonstrate the range of topics within the scope of CMGH. On behalf of the CMGH board of editors, we hope you enjoy this special mini-issue.

More on Barrett's Esophagus

Porcine Esophageal Submucosal Gland Culture Model Shows Capacity for Proliferation and Differentiation

Oct. 22, 2017

We describe a novel porcine 3-dimensional culture model that reproduces esophageal submucosal gland proliferation in vivo associated with cancer and injury.

Late Recurrence of Barrett’s Esophagus After Complete Eradication of Intestinal Metaplasia is Rare: Final Report From Ablation in Intestinal Metaplasia Containing Dysplasia Trial

Sept. 1, 2017

Endoscopic surveillance of patients with BE treated with radiofrequency ablation will likely be of diminishing value as the time since ablation grows.

Cost Effectiveness of Screening Patients With Gastroesophageal Reflux Disease for Barrett’s Esophagus With a Minimally Invasive Cell Sampling Device

Sept. 1, 2017

We found Cytosponge screening with endoscopic confirmation to be a cost-effective strategy.