Pancreatic Neoplasms

Progression of Unresected Intraductal Papillary Mucinous Neoplasms of the Pancreas to Cancer: A Systematic Review and Meta-analysis

Oct. 11, 2017

We found that low-risk IPMNs have almost 8% chance of progressing to pancreatic cancer within 10 years.

Digestive Disease Week® (DDW)

May 6, 2017

Digestive Disease Week® (DDW) is the premier meeting for the GI professional. Every year it attracts approximately 15,000 physicians, researchers and academics from around the world who desire to stay up-to-date in the field.

A Pancreatic Mass Lesion

April 19, 2017

Gastroenterology image challenge highlights the case of a 61-year-old woman with a 3-month history of general fatigue, referred to the hospital for detailed assessment of jaundice.

AGA Members Take Center Stage at UEG Week 2016

Nov. 2, 2016

The Best of DDW® and Rising Stars sessions at the October conference highlighted a number of AGA members and their research.

Why do Pancreatic Tumor Cells Love the Liver?

Nov. 1, 2016

The AGA Journals Blog answers this question by breaking down a new Gastroenterology study.

Upcoming AGA Webinar: Review of Pancreatic Cyst Guidelines

Aug. 25, 2016

Join authors of the guideline and technical review to discuss the evidence behind the guideline.

Administration of Gemcitabine After Pancreatic Tumor Resection in Mice Induces an Antitumor Immune Response Mediated by Natural Killer Cells

Aug. 1, 2016

Transgenic mice with resectable pancreatic tumors might be promising tools to study adjuvant therapy strategies for patients.
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DDSEP 8 - Chapter 3 - Pancreatic Physiology and Disease

April 12, 2016

Focus on a specific GI topic area and master the content most important to you.

Association Between Advances in High-Resolution Cross-Section Imaging Technologies and Increase in Prevalence of Pancreatic Cysts From 2005 to 2014

March 31, 2016

Dr. Maria Moris discusses her manuscript "Association Between Advances in High-Resolution Cross-Section Imaging Technologies and Increase in Prevalence of Pancreatic Cysts From 2005 to 2014." To view abstract http://bit.ly/1Rs3KWC.

Loss of Activin Receptor Type 1B Accelerates Development of Intraductal Papillary Mucinous Neoplasms in Mice With Activated KRAS

Jan. 18, 2016

Loss of ACVR1B accelerates growth of mutant KRAS-induced pancreatic IPMNs in mice; this process appears to involve NOTCH4 and loss of p16.

Now Available: Winter Edition of The New Gastroenterologist

Dec. 9, 2015

The feature story, by Saurabh Mukewar, MD, and Suresh Chari, MD, of the Mayo Clinic, examines the latest in pancreatic cyst management.

Evaluation and Treatment of Possibly Malignant Biliary Stricture

June 3, 2015

Executive summary of valuation and Treatment of Possibly Malignant Biliary Stricture abstract presentation from the 2015 AGA Spring Postgraduate Course.

April GastroSlides: The Physiology and Patho-Physiology of Pancreatic Function

March 25, 2015

With this month's GastroSlides, you’ll find images that illustrate the physiology and patho-physiology of pancreatic function as well as the causes, diagnosis and management of acute and chronic pancreatitis.

Customize Your Teaching of Pancreatic Physiology and Pancreatitis

Nov. 6, 2014

This month's GastroSlides images illustrate the physiology and pathophysiology of pancreatic function, as well as the causes, diagnosis and management of acute and chronic pancreatitis.

A Listeria Vaccine and Depletion of T-Regulatory Cells Activate Immunity Against Early Stage Pancreatic Intraepithelial Neoplasms and Prolong Survival of Mice

June 11, 2014

Watchful Waiting

June 10, 2014

Cutting Is the Cure

June 9, 2014

International Consensus Guidelines on the Management of Pancreatic Mucinous Neoplasms

June 1, 2014

Get a Better Understanding of Pancreatic Physiology and Pancreatitis

Feb. 27, 2014

This month's GastroSlides images illustrate the physiology and pathophysiology of pancreatic function as well as the causes, diagnosis and management of acute and chronic pancreatitis.

MAPK Signaling Is Required for Initiation of Pancreatic Intraepithelial Neoplasia in Mice

Feb. 27, 2014

Publishing in Gastroenterology, Meredith A. Collins and colleagues find that, in iKras* and KC mice, mitogen-activated protein kinase (MAPK) signaling is required for the initiation and maintenance of pancreatic cancer precursor lesions.

Identification and Manipulation of Biliary Metaplasia in Pancreatic Tumors

Jan. 9, 2014

Reporting in Gastroenterology, Kathleen E. DelGiorno and colleagues find that that expression of KrasG12D and SOX17 in mice induces development of metaplasias with a biliary phenotype containing tuft cells.

Treatment of Pancreatic Cystic Neoplasm: Surgery or Conservative?

Dec. 30, 2013

A High-Fat Diet Activates Oncogenic Kras and COX2 to Induce Development of PDAC in Mice

Dec. 5, 2013

Reporting in Gastroenterology, Bincy Philip and colleagues find that, in mice, a high-fat diet can activate oncogenic Kras via cyclo-oxygenase-2 (COX2), leading to pancreatic inflammation and fibrosis and development of pancreatic intraepithelial neoplasia and pancreatic ductal adenocarcinoma (PDAC).

Numb Regulates Acinar Cell Dedifferentiation and Survival During PDA

Nov. 21, 2013

Renee L. Greer and colleagues report in Gastroenterology that Numb is an important regulator of acinar cell differentiation and viability during acinar-to-ductal metaplasia, a common precursor of pancreatic ductal adenocarcinoma (PDA).